Pradeep Varathan

Pradeep Varathan

Full-time Bioinformatics Doctoral Student and Part-time Photographer

Publications

Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation.

Published in Medrxiv, 2023

Our results showed that highly correlated SNPs in the same LD block could have distinct impact on the downstream functions. Although some GWAS lead SNPs …

Recommended citation: Varathan P, Xie L, He B, et al. Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation. Medrxiv : the Preprint Server for Health Sciences. 2023 Oct:2023.10.23.23297399. DOI: 10.1101/2023.10.23.23297399. PMID: 37961458. https://europepmc.org/article/med/37961458

Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains

Published in BMC Medical Genomics, 2022

Large-scale genome-wide association studies have successfully identified many genetic variants significantly associated with Alzheimer’s disease (AD)…

Recommended citation: Varathan, Pradeep, et al. "Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains." BMC Medical Genomics 15.2 (2022): 1-10. https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-022-01245-5

Meta-analysis on big data of bioactive compounds from mangrove ecosystem to treat neurodegenerative disease

Published in Scientometrics, 2020

A systematic review by bibliometric analysis is a streamline method to find out lead molecules as a therapeutic drug molecule to multiple diseases, out of which this review attempts to cover the neurodegenerative diseases …

Recommended citation: George, B., Varathan, P. & Suchithra, T.V. Meta-analysis on big data of bioactive compounds from mangrove ecosystem to treat neurodegenerative disease. Scientometrics 122, 1539–1561 (2020). https://doi.org/10.1007/s11192-020-03355-2 https://link.springer.com/article/10.1007/s11192-020-03355-2?shared-article-renderer#citeas